Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.41 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1913757 | 1.00 | LMNA (0.49) | LMNAMAPK1ALDH1A1TSHRTDP1 | |
| SCHEMBL3117858 | 1.00 | LMNA (0.49) | LMNAMAPK1ALDH1A1TSHRTDP1 | |
| SCHEMBL6453190 | 0.88 | LMNA (0.51) | LMNAMAPK1ALDH1A1TSHRTDP1 | |
| SCHEMBL1913748 | 0.88 | LMNA (0.51) | LMNAMAPK1ALDH1A1TSHRTDP1 | |
| SCHEMBL3125669 | 0.88 | LMNA (0.51) | LMNAMAPK1ALDH1A1TSHRTDP1 | |
| SCHEMBL3114126 | 0.88 | CACNA2D1 (0.45) | MAPK1MTNR1AMTNR1BCACNA2D1CACNB3 | |
| SCHEMBL1913741 | 0.88 | CACNA2D1 (0.45) | MAPK1MTNR1AMTNR1BCACNA2D1CACNB3 | |
| SCHEMBL7174635 | 0.88 | CACNA2D1 (0.45) | MAPK1MTNR1AMTNR1BCACNA2D1CACNB3 | |
| SCHEMBL3114806 | 0.88 | CACNA2D1 (0.47) | MAPK1TDP1MTNR1AMTNR1BPPARG | |
| SCHEMBL1913698 | 0.88 | CACNA2D1 (0.47) | MAPK1TDP1MTNR1AMTNR1BPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117045653-A | Diseases and treatments associated with toxic aldehydes | 奥尔德拉医疗公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-111135171-B | Diseases and treatments associated with toxic aldehydes | 奥尔德拉医疗公司 | 2023-09-08 | — | — | CN | disclosed |
| EP-1572188-A1 | PREGABALIN DERIVATIVES FOR THE TREATMENT OF FIBROMYALGIA AND OTHER DISORDERS | Warner-Lambert Company LLC (US) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004054566-A1 | PREGABALIN DERIVATIVES FOR THE TREATMENT OF FIBROMYALGIA AND OTHER DISORDERS | WARNER-LAMBERT COMPANY LLC (US) | 2004-07-01 | — | — | WO | disclosed |