Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 7/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6454491 | 1.00 | MAT2A (0.34) | MAT2AIDO1SLC34A1MEN1KMT2A | |
| SCHEMBL6452484 | 0.92 | MAT2A (0.33) | MAT2AIDO1SLC34A1 | |
| SCHEMBL6452481 | 0.92 | MAT2A (0.33) | MAT2AIDO1SLC34A1 | |
| SCHEMBL6453696 | 0.90 | MAT2A (0.32) | MAT2AIDO1 | |
| SCHEMBL6453689 | 0.90 | MAT2A (0.32) | MAT2AIDO1 | |
| SCHEMBL6459307 | 0.89 | MAT2A (0.32) | MAT2A | |
| SCHEMBL6459313 | 0.89 | MAT2A (0.32) | MAT2A | |
| SCHEMBL6453909 | 0.88 | MAT2A (0.31) | MAT2A | |
| SCHEMBL6460979 | 0.88 | MAT2A (0.31) | MAT2A | |
| SCHEMBL6453903 | 0.88 | MAT2A (0.31) | MAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |