Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6454747 | 1.00 | DRD2 (0.38) | DRD2DGAT1GRIN2BUSP30SLC6A2 | |
| SCHEMBL6453646 | 0.88 | DRD2 (0.37) | DRD2DGAT1GRIN2BSLC6A2SLC6A4 | |
| SCHEMBL6453649 | 0.88 | DRD2 (0.37) | DRD2DGAT1GRIN2BSLC6A2SLC6A4 | |
| SCHEMBL6455252 | 0.87 | DRD2 (0.36) | DRD2DGAT1GRIN2BSLC6A2SLC6A4 | |
| SCHEMBL6455248 | 0.87 | DRD2 (0.36) | DRD2DGAT1GRIN2BSLC6A2SLC6A4 | |
| SCHEMBL6455247 | 0.87 | DRD2 (0.36) | DRD2DGAT1GRIN2BSLC6A2SLC6A4 | |
| SCHEMBL6463704 | 0.85 | DRD2 (0.47) | DRD2GRIN2BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6456399 | 0.85 | DRD2 (0.47) | DRD2GRIN2BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6456394 | 0.85 | DRD2 (0.47) | DRD2GRIN2BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6453170 | 0.84 | EPHX2 (0.39) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |