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Hydrochloric Acid

Hydrochloric Acid

SCHEMBL6455221

CC1=C2c3c(-c4ccc(C(C)(C)C)cc4)cccc3C1[Hf+2]C1C(C)=C(c3c(-c4ccc(C(C)(C)C)cc4)cccc31)[Si]2(C)C.[Cl-].[Cl-]

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 1/20 0.31
▸ CREBBP Q92793 1/20 0.31
▸ KIF11 P52732 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7583888 0.85 PDCD1 (0.31) —
Hydrochloric Acid SCHEMBL4315257 0.82 BRD4 (0.31) BRD4CREBBPKIF11
SCHEMBL6637535 0.81 BRD4 (0.32) BRD4CREBBP
SCHEMBL7187056 0.81 BRD4 (0.32) BRD4CREBBP
SCHEMBL7187674 0.81 BRD4 (0.32) BRD4CREBBP
SCHEMBL5914834 0.80 BRD4 (0.31) BRD4CREBBP
Hydrochloric Acid SCHEMBL17922857 0.80 — —
Hydrochloric Acid SCHEMBL3689419 0.73 BRD4 (0.30) BRD4CREBBP
Hydrochloric Acid SCHEMBL4275886 0.73 PBRM1 (0.33) —
Hydrochloric Acid SCHEMBL4317151 0.72 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1054911-B1 CATALYST SYSTEM, METHOD FOR THE PRODUCTION THEREOF AND ITS USE FOR THE POLYMERIZATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2003-01-22 — — EP claimed
US-6949614-B1 Catalyst system BASELL POLYOLEFINE GMBH (DE) 2005-09-27 — — US disclosed