SCHEMBL645539

SCHEMBL645539

Cc1ccc2ccc[c]c2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.48
TDP1 Q9NUW8 2/20 0.48
CYP1A2 P05177 8/20 0.47
ALDH1A1 P00352 4/20 0.39
ACHE P22303 1/20 0.35
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
THRB P10828 1/20 0.34
ALOX15 P16050 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NQO2 P16083 1/20 0.34
MAOA P21397 1/20 0.32
HPGD P15428 2/20 0.31
HSD17B10 Q99714 2/20 0.31
NCK1 P16333 1/20 0.31
BACE1 P56817 1/20 0.31
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
CA12 O43570 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2701498 0.84 CYP2A6 (0.52) CYP2A6TDP1CYP1A2ALDH1A1CYP3A4
SCHEMBL2701886 0.84 CYP2A6 (0.52) CYP2A6TDP1CYP1A2ALDH1A1CYP3A4
SCHEMBL645977 0.83 CYP2A6 (0.48) CYP2A6TDP1CYP1A2ALDH1A1ACHE
SCHEMBL2318612 0.77 ESR1 (0.35) TDP1CYP1A2ALDH1A1CYP3A4ALOX15
SCHEMBL28146675 0.77 CYP1A2 (0.38) CYP2A6TDP1CYP1A2ALDH1A1ACHE
SCHEMBL18317277 0.76 CYP1A2 (0.50) CYP2A6TDP1CYP1A2ALDH1A1THRB
SCHEMBL756551 0.76 CYP2A6 (0.32) CYP2A6
SCHEMBL2257839 0.76 CYP3A4 (0.50) TDP1ALDH1A1ACHETP53CYP3A4
SCHEMBL9169786 0.76 CYP2A6 (0.34) CYP2A6TDP1CYP1A2ALDH1A1CYP3A4
SCHEMBL3483286 0.75 EGFR (0.37) CYP1A2ALDH1A1CYP3A4HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 294 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117983302-A Catalyst containing ferrocene PNP ligand for ethylene selective tetramerization and preparation method and application thereof 华东理工大学 2024-05-07 CN claimed
US-4125619-A ANTITHROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) 1978-11-14 US claimed
US-4104392-A N2 -naphthalenesulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof, and antithrombotic compositions and methods employing them MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) 1978-08-01 US claimed
US-4096255-A ANTICOAGULANTS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) 1978-06-20 US claimed
US-4073916-A THROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) 1978-02-14 US claimed
US-4073914-A THROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) 1978-02-14 US claimed
US-4072744-A SUPPRESSION OF THROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) 1978-02-07 US claimed
US-4070457-A ANTITHROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) 1978-01-24 US claimed
US-4049645-A ANTITHROMBOTIC AGENTS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) 1977-09-20 US claimed
US-4036955-A TREATMENT OF THROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) 1977-07-19 US claimed
CN-117983302-A Catalyst containing ferrocene PNP ligand for ethylene selective tetramerization and preparation method and application thereof 华东理工大学 2024-05-07 CN disclosed
US-11681222-B2 Fluorine-containing polymer, purification method, and radiation-sensitive resin composition JSR CORPORATION (JP) 2023-06-20 US disclosed
EP-3710439-B1 KRAS G12C INHIBITORS MIRATI THERAPEUTICS INC (US) 2023-02-15 EP disclosed
US-11581567-B2 Lithium ion battery and electrolyte thereof CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED (CN) 2023-02-14 US disclosed
US-20220137508-A9 FLUORINE-CONTAINING POLYMER, PURIFICATION METHOD, AND RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2022-05-05 US disclosed
US-3975279-A B-(HALOPROPYL)-THIONOPHOSPHATE AND A STYRENE OXIDE ETHYL CORPORATION (US) 1976-08-17 US disclosed
US-3958955-A CYCLOPENTADIENYL MANGANESE TRICARBONYL ANTIKNOCK ETHYL CORPORATION (US) 1976-05-25 US disclosed
US-3957892-A A CONJUGATED DIENE AND A PHENOL ETHYL CORPORATION (US) 1976-05-18 US disclosed
US-3950145-A ANTIKNOCK ETHYL CORPORATION (US) 1976-04-13 US disclosed
US-3948618-A GASOLINE; A CYCLOPENTADIENYL MANGANESE TRICARBONYL ANTIKNOCK AGENT ETHYL CORPORATION (US) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11581567-B2 Lithium ion battery and electrolyte thereof PLCB1, PLCB3, LAGE3 CYP2A6 4413/4885TDP1 4005/4885CYP1A2 4570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.