Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 16/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 16/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6450768 | 1.00 | CYP11B1 (0.36) | CYP11B1CYP11B2KDM1AFASNGAA | |
| SCHEMBL6450770 | 1.00 | CYP11B1 (0.36) | CYP11B1CYP11B2KDM1AFASNGAA | |
| SCHEMBL6455475 | 1.00 | CYP11B1 (0.36) | CYP11B1CYP11B2KDM1AFASNGAA | |
| SCHEMBL6453439 | 0.99 | CYP11B1 (0.37) | CYP11B1CYP11B2KDM1AFASN | |
| SCHEMBL6453446 | 0.99 | CYP11B1 (0.37) | CYP11B1CYP11B2KDM1AFASN | |
| SCHEMBL6460644 | 0.96 | CYP11B1 (0.37) | CYP11B1CYP11B2KDM1AFASN | |
| SCHEMBL6460641 | 0.96 | CYP11B1 (0.37) | CYP11B1CYP11B2KDM1AFASN | |
| SCHEMBL6454455 | 0.92 | CYP11B1 (0.38) | CYP11B1CYP11B2KDM1AFASN | |
| SCHEMBL6454452 | 0.92 | CYP11B1 (0.38) | CYP11B1CYP11B2KDM1AFASN | |
| SCHEMBL6461100 | 0.90 | KIF11 (0.38) | CYP11B1CYP11B2KDM1AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |