Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6455660 | 1.00 | KDM1A (0.41) | KDM1AGRIN1GRIN2BNAAAPTGS2 | |
| SCHEMBL6454444 | 0.92 | KDM1A (0.40) | KDM1AGRIN1GRIN2BNAAAPTGS2 | |
| SCHEMBL6454438 | 0.92 | KDM1A (0.40) | KDM1AGRIN1GRIN2BNAAAPTGS2 | |
| SCHEMBL6452388 | 0.90 | KDM1A (0.32) | KDM1ANAAAHIF1A | |
| SCHEMBL6452393 | 0.90 | KDM1A (0.32) | KDM1ANAAAHIF1A | |
| SCHEMBL6459828 | 0.90 | KDM1A (0.39) | KDM1AGRIN1GRIN2BNAAAPTGS2 | |
| SCHEMBL6459824 | 0.90 | KDM1A (0.39) | KDM1AGRIN1GRIN2BNAAAPTGS2 | |
| SCHEMBL6455576 | 0.90 | CTSK (0.37) | KDM1ANAAA | |
| SCHEMBL6455580 | 0.90 | CTSK (0.37) | KDM1ANAAA | |
| SCHEMBL6459360 | 0.89 | KDM1A (0.38) | KDM1AGRIN1GRIN2BNAAAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |