Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 2/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6456144 | 1.00 | PDE4B (0.30) | PDE4BKDM1ABACE1GRM2FPR2 | |
| SCHEMBL6455848 | 0.94 | MGLL (0.31) | — | |
| SCHEMBL6455847 | 0.94 | MGLL (0.31) | — | |
| SCHEMBL6453556 | 0.93 | MGLL (0.31) | — | |
| SCHEMBL6453559 | 0.93 | MGLL (0.31) | — | |
| SCHEMBL6463441 | 0.92 | MGLL (0.32) | — | |
| SCHEMBL6460567 | 0.92 | MGLL (0.32) | — | |
| SCHEMBL6463439 | 0.92 | MGLL (0.32) | — | |
| SCHEMBL6460570 | 0.92 | MGLL (0.32) | — | |
| SCHEMBL6453460 | 0.92 | GRIN1 (0.32) | PDE4BKDM1AGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |