Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 2/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6456600 | 1.00 | FASN (0.35) | FASNKDM1AGRM2APPSLC6A2 | |
| SCHEMBL6455560 | 0.89 | KDM1A (0.44) | FASNKDM1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6455561 | 0.89 | KDM1A (0.44) | FASNKDM1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6455023 | 0.89 | GRM2 (0.35) | KDM1AGRM2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6455027 | 0.89 | GRM2 (0.35) | KDM1AGRM2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18134246 | 0.89 | FASN (0.39) | FASNKDM1AGRM2APPPDE4D | |
| SCHEMBL6455076 | 0.87 | FASN (0.34) | FASNAPP | |
| SCHEMBL6455071 | 0.87 | FASN (0.34) | FASNAPP | |
| SCHEMBL6460319 | 0.87 | GRM2 (0.34) | KDM1AGRM2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6456899 | 0.87 | FASN (0.37) | FASNGRM2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |