SCHEMBL6456771

SCHEMBL6456771

CC=CCOc1ccc2cc(C3CCC4CC(C)CCC4C3)ccc2c1

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 11/20 0.37
SLC6A2 P23975 10/20 0.37
SLC6A3 Q01959 10/20 0.37
HRH3 Q9Y5N1 2/20 0.31
RAB9A P51151 1/20 0.31
HTR1A P08908 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6456761 1.00 SLC6A4 (0.37) SLC6A4SLC6A2SLC6A3HRH3RAB9A
SCHEMBL6456766 1.00 SLC6A4 (0.37) SLC6A4SLC6A2SLC6A3HRH3RAB9A
SCHEMBL6456722 0.87 CA12 (0.40) SLC6A4SLC6A2SLC6A3
SCHEMBL6456728 0.87 CA12 (0.40) SLC6A4SLC6A2SLC6A3
SCHEMBL6451423 0.86 SLC6A4 (0.38) SLC6A4SLC6A2SLC6A3
SCHEMBL6451417 0.86 SLC6A4 (0.38) SLC6A4SLC6A2SLC6A3
SCHEMBL6451411 0.86 SLC6A4 (0.38) SLC6A4SLC6A2SLC6A3
SCHEMBL6460575 0.86
SCHEMBL6460569 0.86
SCHEMBL6460565 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6913797-B1 Decahydronaphthalene derivative DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-07-05 US disclosed
EP-1108700-A1 DECAHYDRONAPHTHALENE DERIVATIVE DAINIPPON INK AND CHEMICALS, INC. (JP) 2001-06-20 EP disclosed