Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6456728 | 1.00 | CA12 (0.40) | CA12CA1CA9SLC6A2SLC6A4 | |
| SCHEMBL6456771 | 0.87 | SLC6A4 (0.37) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6456761 | 0.87 | SLC6A4 (0.37) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6456766 | 0.87 | SLC6A4 (0.37) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6454942 | 0.86 | SLC6A2 (0.39) | CA12CA1CA9SLC6A2SLC6A4 | |
| SCHEMBL6454948 | 0.86 | SLC6A2 (0.39) | CA12CA1CA9SLC6A2SLC6A4 | |
| SCHEMBL6450731 | 0.86 | HTR2C (0.31) | CA12CA1CA9SLC6A2SLC6A4 | |
| SCHEMBL6450725 | 0.86 | HTR2C (0.31) | CA12CA1CA9SLC6A2SLC6A4 | |
| SCHEMBL6451402 | 0.85 | ALDH1A1 (0.38) | CA12CA1CA9ALDH1A1TSHR | |
| SCHEMBL6451408 | 0.85 | ALDH1A1 (0.38) | CA12CA1CA9ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |