SCHEMBL64568

SCHEMBL64568

Nc1nc2c(c(=O)[nH]1)NCN2CCOCP(=O)(O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 14/20 1.00
POLB P06746 2/20 0.41
PNP P00491 1/20 0.40
POLA1 P09884 1/20 0.39
POLG P54098 1/20 0.39
TYMP P19971 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL3497655 0.99 HPRT1 (0.98) HPRT1POLBPNPPOLA1POLG
SCHEMBL9054351 0.93 HPRT1 (0.87) HPRT1PNP
SCHEMBL9053851 0.92 HPRT1 (0.85) HPRT1PNP
SCHEMBL15531987 0.86 HPRT1 (0.74) HPRT1
SCHEMBL10430809 0.85 HPRT1 (0.74) HPRT1POLBPNP
SCHEMBL8899140 0.85 HPRT1 (0.74) HPRT1PNP
SCHEMBL9417162 0.84 HPRT1 (0.72) HPRT1POLBPNP
SCHEMBL9056240 0.83 HPRT1 (0.71) HPRT1
SCHEMBL6834255 0.82 HPRT1 (0.70) HPRT1PNP
SCHEMBL6834509 0.82 HPRT1 (0.70) HPRT1PNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 270 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12497435-B2 Multimerization of IL-15/IL-15R-alpha-fc complexes to enhance immunotherapy MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2025-12-16 US claimed
US-20220106375-A1 MULTIMERIZATION OF IL-15/IL-15R-ALPHA-FC COMPLEXES TO ENHANCE IMMUNOTHERAPY MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2022-04-07 US claimed
EP-3908314-A1 MULTIMERIZATION OF IL-15/IL-15R-ALPHA-FC COMPLEXES TO ENHANCE IMMUNOTHERAPY Memorial Sloan Kettering Cancer Center (US) 2021-11-17 EP claimed
WO-2020146835-A1 MULTIMERIZATION OF IL-15/IL-15R-ALPHA-FC COMPLEXES TO ENHANCE IMMUNOTHERAPY MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2020-07-16 WO claimed
JP-2012500104-A 2012-01-05 JP claimed
EP-2320991-A2 DEVICE AND METHOD FOR DRUG EVALUATION AND LOCAL TREATMENT Third Rock Ventures (US) 2011-05-18 EP claimed
WO-2010022252-A2 DEVICE AND METHOD FOR DRUG EVALUATION AND LOCAL TREATMENT THIRD ROCK VENTURES (US) 2010-02-25 WO claimed
US-6964968-B2 Method for the treatment or prevention of viral infection using nucleoside analogues SHIRE BIOCHEM, INC. (CA) 2005-11-15 US claimed
US-6583149-B1 2-hydroxymethyl-4-(cytosin-1'-yl)-1,3-Dioxolane BIOCHEM PHARMA INC. (CA) 2003-06-24 US claimed
WO-1996040704-A1 PYRAZOLE-RELATED DERIVATIVES ENDOWED WITH ANTITUMOR AND ANTIVIRAL ACTIVITIES, PROCEDURES FOR THEIR PREPARATION, PHARMACEUTICAL FORMULATIONS CONTAINING THEM SARDINIAN ANTIVIRAL RESEARCH CONSORTIUM SARC S.C.R.L. (IT) 1996-12-19 WO claimed
EP-0269947-A1 Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) 1988-06-08 EP claimed
US-12521397-B2 Nucleotide analogs THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-01-13 US disclosed
US-12497435-B2 Multimerization of IL-15/IL-15R-alpha-fc complexes to enhance immunotherapy MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2025-12-16 US disclosed
US-20250352777-A1 SUBMUCOSAL BIORESORBABLE DRUG ELUTING PLATFORM INTERSECT ENT INC (US) 2025-11-20 US disclosed
US-12403291-B2 Submucosal bioresorbable drug eluting platform INTERSECT ENT, INC. (US) 2025-09-02 US disclosed
EP-0630381-A1 ANTIVIRAL ACYCLIC PHOSPHONOMETHOXYALKYL SUBSTITUTED, ALKENYL AND ALKYNYL PURINE AND PYRIMIDINE DERIVATIVES. ACAD OF SCIENCE CZECH REPUBLIC (CS) 1994-12-28 EP disclosed
US-5302585-A Viricides, HIV virus INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) 1994-04-12 US disclosed
WO-1993007157-A1 ANTIVIRAL ACYCLIC PHOSPHONOMETHOXYALKYL SUBSTITUTED, ALKENYL AND ALKYNYL PURINE AND PYRIMIDINE DERIVATIVES INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OFTHE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) 1993-04-15 WO disclosed
EP-0452935-A1 Chiral 2-(phosphonomethoxy)propyl guanines as antiviral agents INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) 1991-10-23 EP disclosed
EP-0269947-A1 Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) 1988-06-08 EP disclosed