SCHEMBL9417162

SCHEMBL9417162

Nc1nc2c(c(=O)[nH]1)NCN2OCCOCP(=O)(O)O

nearest known ligand 0.72

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 14/20 0.72
PNP P00491 3/20 0.40
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9857606 0.93 HPRT1 (0.69) HPRT1PNP
SCHEMBL9576807 0.89 HPRT1 (0.67) HPRT1PNP
Ammonia Solution, Strong SCHEMBL9126239 0.88 HPRT1 (0.65) HPRT1PNP
SCHEMBL9858182 0.85 HPRT1 (0.62) HPRT1PNP
SCHEMBL9684323 0.85 HPRT1 (0.62) HPRT1PNP
SCHEMBL9417138 0.84 HPRT1 (0.53) HPRT1PNPPOLB
SCHEMBL9683454 0.84 HPRT1 (0.61) HPRT1PNP
SCHEMBL64568 0.84 HPRT1 (1.00) HPRT1PNPPOLB
Phosphoric Acid SCHEMBL3497655 0.83 HPRT1 (0.98) HPRT1PNPPOLB
SCHEMBL9054351 0.82 HPRT1 (0.87) HPRT1PNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0319228-B1 Novel compounds BEECHAM GROUP PLC (GB) 1994-11-02 EP claimed
US-5247085-A Phosphonate containing purine compounds BEECHAM GROUP P.L.C. (GB) 1993-09-21 US claimed
EP-0319228-A2 Novel compounds BEECHAM GROUP PLC (GB) 1989-06-07 EP claimed
CN-116940360-A Application of 5-nitro-8-hydroxyquinoline 江苏亚虹医药科技股份有限公司 2023-10-24 CN disclosed
EP-0319228-B1 Novel compounds BEECHAM GROUP PLC (GB) 1994-11-02 EP disclosed
US-5247085-A Phosphonate containing purine compounds BEECHAM GROUP P.L.C. (GB) 1993-09-21 US disclosed
EP-0319228-A2 Novel compounds BEECHAM GROUP PLC (GB) 1989-06-07 EP disclosed