Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL6456873

N.O=C(O)n1nnc2ccccc21.c1cc2cc(c1)CC2

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 8/20 0.54
MGAM O43451 7/20 0.54
AMY1A P0DUB6 7/20 0.54
SI P14410 7/20 0.54
MGAM2 Q2M2H8 7/20 0.54
KMT2A Q03164 3/20 0.54
F2 P00734 2/20 0.54
HPGD P15428 2/20 0.54
SLC9A1 P19634 1/20 0.54
FAAH O00519 3/20 0.48
MGLL Q99685 3/20 0.48
DGAT1 O75907 1/20 0.47
KCNMA1 Q12791 1/20 0.47
F12 P00748 4/20 0.46
GLA P06280 1/20 0.45
THRB P10828 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL3505685 0.86 GAA (0.69) GAAMGAMAMY1ASIMGAM2
SCHEMBL170673 0.84 GAA (0.71) GAAMGAMAMY1ASIMGAM2
SCHEMBL3840404 0.83 GAA (0.69) GAAMGAMAMY1ASIMGAM2
Water SCHEMBL27547496 0.83 GAA (0.69) GAAMGAMAMY1ASIMGAM2
Hydrochloric Acid SCHEMBL10363645 0.83 GAA (0.69) GAAMGAMAMY1ASIMGAM2
Methyl Alcohol SCHEMBL28226904 0.81 GAA (0.67) GAAMGAMAMY1ASIMGAM2
Malonic Acid SCHEMBL8211367 0.77 GAA (0.61) GAAMGAMAMY1ASIMGAM2
Allyl Alcohol SCHEMBL28517173 0.74 GAA (0.56) GAAMGAMAMY1ASIMGAM2
Benzotriazole SCHEMBL5506516 0.72 GAA (0.55) GAAMGAMAMY1ASIMGAM2
SCHEMBL7516240 0.72 GAA (0.55) GAAMGAMAMY1ASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1585541-A2 PHARMACEUTICAL COMPOSITIONS COMPRISING INSULIN AND LEGENDS OF INSULIN HEXAMER NOVO NORDISK A/S (DK) 2005-10-19 EP disclosed
WO-2004056347-A2 PHARMACEUTICAL COMPOSITIONS COMPRISING INSULIN AND LEGENDS OF INSULIN HEXAMER NOVO NORDISK A/S (DK) 2004-07-08 WO disclosed