Malonic Acid

Malonic Acid

SCHEMBL8211367

O=C(O)CC(=O)O.O=C(O)n1nnc2ccccc21

nearest known ligand 0.61

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 6/20 0.61
MGAM O43451 5/20 0.61
AMY1A P0DUB6 5/20 0.61
SI P14410 5/20 0.61
MGAM2 Q2M2H8 5/20 0.61
F2 P00734 2/20 0.61
HPGD P15428 1/20 0.61
SLC9A1 P19634 1/20 0.61
KMT2A Q03164 1/20 0.61
DGAT1 O75907 1/20 0.54
EGLN3 Q9H6Z9 1/20 0.54
ASAH1 Q13510 2/20 0.53
KCNMA1 Q12791 1/20 0.53
F12 P00748 3/20 0.51
FAAH O00519 2/20 0.50
MGLL Q99685 2/20 0.50
CYP4Z1 Q86W10 3/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2C8 P10632 1/20 0.49
CYP2B6 P20813 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL170673 0.91 GAA (0.71) GAAMGAMAMY1ASIMGAM2
Water SCHEMBL27547496 0.90 GAA (0.69) GAAMGAMAMY1ASIMGAM2
SCHEMBL3840404 0.90 GAA (0.69) GAAMGAMAMY1ASIMGAM2
Hydrochloric Acid SCHEMBL10363645 0.90 GAA (0.69) GAAMGAMAMY1ASIMGAM2
Ammonia Solution, Strong SCHEMBL3505685 0.90 GAA (0.69) GAAMGAMAMY1ASIMGAM2
Methyl Alcohol SCHEMBL28226904 0.88 GAA (0.67) GAAMGAMAMY1ASIMGAM2
Allyl Alcohol SCHEMBL28517173 0.83 GAA (0.56) GAAMGAMAMY1ASIMGAM2
SCHEMBL3544941 0.82 EGLN3 (0.60) GAAMGAMAMY1ASIMGAM2
SCHEMBL8221643 0.80 ASAH1 (0.64) GAAMGAMAMY1ASIMGAM2
Benzotriazole SCHEMBL5506516 0.78 GAA (0.55) GAAMGAMAMY1ASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0809150-B1 Photosensitive aqueous developable thick film composition employing vinylpyrrolidone polymer DU PONT (US) 2000-07-19 EP disclosed