Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6457441 | 1.00 | FASN (0.37) | FASNCYP3A4CYP2C9APPSLC6A2 | |
| SCHEMBL6460347 | 0.90 | FASN (0.41) | FASNCYP3A4CYP2C9APPSLC6A2 | |
| SCHEMBL6453237 | 0.90 | FASN (0.37) | FASNCYP3A4CYP2C9APPCYP2D6 | |
| SCHEMBL6460352 | 0.90 | FASN (0.41) | FASNCYP3A4CYP2C9APPSLC6A2 | |
| SCHEMBL6453235 | 0.90 | FASN (0.37) | FASNCYP3A4CYP2C9APPCYP2D6 | |
| SCHEMBL6456896 | 0.89 | FASN (0.38) | FASNCYP3A4CYP2C9APPPDE3B | |
| SCHEMBL6456894 | 0.89 | FASN (0.38) | FASNCYP3A4CYP2C9APPPDE3B | |
| SCHEMBL6452082 | 0.87 | FASN (0.36) | FASNCYP3A4CYP2C9APP | |
| SCHEMBL6452085 | 0.87 | FASN (0.36) | FASNCYP3A4CYP2C9APP | |
| SCHEMBL13614719 | 0.86 | FASN (0.43) | FASNCYP3A4CYP2C9APPPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |