Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | DBH | P09172 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6458497 | 1.00 | KDM1A (0.40) | KDM1AMAOAMAOBDBHKDM4E | |
| SCHEMBL6452126 | 0.87 | HCRTR1 (0.39) | — | |
| SCHEMBL6459662 | 0.87 | HCRTR1 (0.35) | — | |
| SCHEMBL6452121 | 0.87 | HCRTR1 (0.39) | — | |
| SCHEMBL6459665 | 0.87 | HCRTR1 (0.35) | — | |
| SCHEMBL6452996 | 0.85 | SLC6A2 (0.38) | KDM1AMAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL6452994 | 0.85 | SLC6A2 (0.38) | KDM1AMAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL6463714 | 0.83 | DBH (0.34) | DBH | |
| SCHEMBL12032041 | 0.83 | SLC6A2 (0.36) | KDM1AMAOAMAOBALDH1A1CHRM3 | |
| SCHEMBL6463711 | 0.83 | DBH (0.34) | DBH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |