Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL384025 | 0.84 | CYP1A2 (0.56) | CYP1A2CTDSP1PLAUKDM4EMAPKAPK2 | |
| SCHEMBL2781984 | 0.77 | ALDH1A1 (0.33) | CYP1A2TSHRHPGDHSD17B10TDP1 | |
| SCHEMBL643662 | 0.74 | MEN1 (0.33) | KDM4EHPGDMEN1KMT2A | |
| SCHEMBL6631028 | 0.74 | PTPN22 (0.50) | CYP1A2KDM4EHPGDALOX15RECQL | |
| SCHEMBL645983 | 0.74 | CYP2A6 (0.54) | CYP1A2KDM4ETSHRHSD17B10ALDH1A1 | |
| SCHEMBL647103 | 0.74 | BACE1 (0.34) | CYP1A2ALDH1A1 | |
| SCHEMBL466417 | 0.74 | CYP2A6 (0.54) | CYP1A2PLAUTSHRHPGDHSD17B10 | |
| SCHEMBL2253188 | 0.74 | ALDH1A1 (0.54) | CYP1A2CTDSP1PLAUKDM4ETSHR | |
| 1-Naphthol SCHEMBL28322906 | 0.74 | CYP1A2 (0.94) | CYP1A2CTDSP1PLAUKDM4EMAPKAPK2 | |
| 1-Naphthol SCHEMBL28123317 | 0.74 | CYP1A2 (0.94) | CYP1A2CTDSP1PLAUKDM4EMAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 410 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745719-A2 | Use of carbohydrate compounds as auxiliary agents in the dyeing or printing of fibrous materials | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-04 | — | — | EP | claimed |
| CN-118103357-A | FABP4/5 inhibitors, methods of use and methods of preparation | 塞洛拉姆股份有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-117980305-A | Spirocyclic pyridine-1, 5-diones exhibiting MNK inhibition and methods of use thereof | 4E治疗公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-117679487-A | Inhibition of pulmonary fibrosis with Nutlin-3a and peptides | 得克萨斯州大学系统董事会 | 2024-03-12 | — | — | CN | disclosed |
| US-11883386-B2 | Prolyl hydroxylase inhibitors and methods of use | AKEBIA THERAPEUTICS, INC. (US) | 2024-01-30 | — | — | US | disclosed |
| CN-110201144-B | Inhibition of pulmonary fibrosis with Nutlin-3a and peptides | 得克萨斯州大学系统董事会 | 2024-01-02 | — | — | CN | disclosed |
| CN-117279909-A | Novel liver selective polyadenylation polymerase inhibitors and methods of use thereof | 巴鲁克斯布伦博格研究所 | 2023-12-22 | — | — | CN | disclosed |
| WO-2023172486-A1 | METAL POLYMER COMPLEXES METHODS FOR CARBON DIOXIDE CAPTURE | LEHIGH UNIVERSITY (US) | 2023-09-14 | — | — | WO | disclosed |
| EP-3768682-B1 | 2-({2H,3H-[1,4]DIOXINO[2,3-G]QUINOLIN-7-YL}SULFANYL)ACETAMIDE DERIVATIVES AS BCR-ABL KINASE INHIBITORS FOR THE TREATMENT OF CANCER | ALLCRON PHARMA INC (US) | 2023-07-05 | — | — | EP | disclosed |
| US-20230201178-A1 | PROLYL HYDROXYLASE INHIBITORS AND METHODS OF USE | KREOS CAPITAL VII (UK) LIMITED (GB) | 2023-06-29 | — | — | US | disclosed |
| US-5834501-A | TREATING DIABETES OR HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 1998-11-10 | — | — | US | disclosed |
| US-5766267-A | USING FIBER REACTIVE DYES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-06-16 | — | — | US | disclosed |
| US-5750681-A | Bicyclic beta-lactams and process therefor | UNIVERSITY OF NOTRE DAME DU LAC (US) | 1998-05-12 | — | — | US | disclosed |
| US-5739345-A | HYPOGLYCEMIC AND ANTIDIABETIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1998-04-14 | — | — | US | disclosed |
| US-5624935-A | ANTIDIABETIC AGENTS, HYPOGLYCEMIC AGENTS OR ANTILIPEMIC AGENTS | SANKYO COMPANY, LIMITED | 1997-04-29 | — | — | US | disclosed |
| EP-0745600-A1 | Benzimidazole derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1996-12-04 | — | — | EP | disclosed |
| EP-0745719-A2 | Use of carbohydrate compounds as auxiliary agents in the dyeing or printing of fibrous materials | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-04 | — | — | EP | disclosed |
| CN-1118781-A | Heterocyclic compound with activity against diabetes and preparation and application of same | MITSUTAKA CO LTD (JP) | 1996-03-20 | — | — | CN | disclosed |
| EP-0676398-A2 | Heterocyclic compounds having anti-diabetic activity, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1995-10-11 | — | — | EP | disclosed |
| US-5216138-A | With vinyl sulfonyl group | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11883386-B2 | Prolyl hydroxylase inhibitors and methods of use | HIF1AN, EGLN3, HIF1A | CYP1A2 1465/4885CTDSP1 803/4885PLAU 1093/4885 |
| US-20230201178-A1 | PROLYL HYDROXYLASE INHIBITORS AND METHODS OF USE | HIF1AN, EGLN3, HIF1A | CYP1A2 1465/4885CTDSP1 803/4885PLAU 1093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.