Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | AXL | P30530 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29664560 | 1.00 | TDP1 (0.54) | TDP1AXLPKML3MBTL1KDM4E | |
| SCHEMBL28199188 | 0.88 | GRM5 (0.50) | TDP1AXLPKML3MBTL1KDM4E | |
| SCHEMBL812065 | 0.86 | KDM4E (0.59) | TDP1PKML3MBTL1KDM4EPOLB | |
| SCHEMBL27862967 | 0.83 | TSHR (0.57) | L3MBTL1KDM4EATMLMNATSHR | |
| SCHEMBL30071543 | 0.83 | TSHR (0.57) | L3MBTL1KDM4EATMLMNATSHR | |
| SCHEMBL14840898 | 0.83 | TDP1 (0.47) | TDP1PKML3MBTL1KDM4EPOLB | |
| SCHEMBL812066 | 0.83 | AXL (0.47) | TDP1AXLPKML3MBTL1KDM4E | |
| SCHEMBL7649536 | 0.82 | TDP1 (0.59) | TDP1PKML3MBTL1KDM4EPOLB | |
| SCHEMBL29694130 | 0.82 | SLC6A3 (0.55) | TDP1AXLPKML3MBTL1KDM4E | |
| SCHEMBL5234641 | 0.82 | SLC6A3 (0.55) | TDP1AXLPKML3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439794-A | Spectroscopically or photoactively determination when bound to Dna | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1995-08-08 | — | — | US | claimed |
| US-5157032-A | Spectroscopically or photoactively determinable | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1992-10-20 | — | — | US | claimed |
| US-5112974-A | Targets tumor cells for radiation treatment, metal complexes with amines or imines | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1992-05-12 | — | — | US | claimed |
| WO-1990005732-A1 | MIXED LIGAND COMPLEXES AND USES THEREOF AS BINDING AGENTS AND PROBRES TO DNA | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OFNEW YORK (US) | 1990-05-31 | — | — | WO | claimed |
| CN-118176175-A | Method for producing perfluoroalkyl group-containing aromatic compound | 大金工业株式会社 | 2024-06-11 | — | — | CN | disclosed |
| EP-2029570-B1 | FUSED THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA SA (BE) | 2014-10-15 | — | — | EP | disclosed |
| EP-2390241-B1 | METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2014-10-01 | — | — | EP | disclosed |
| US-8324204-B2 | Fused thiophene derivatives as kinase inhibitors | UCB PHARMA SA (BE) | 2012-12-04 | — | — | US | disclosed |
| US-20120208190-A1 | LUMINESCENT METAL ION COMPLEXES | BIOSEARCH TECHNOLOGIES, INC. (US) | 2012-08-16 | — | — | US | disclosed |
| US-8119781-B2 | Luminescent metal ion complexes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2012-02-21 | — | — | US | disclosed |
| US-20100305066-A1 | Fused Thiophene Derivatives as Kinase Inhibitors | UCB PHARMA S.A. (BE) | 2010-12-02 | — | — | US | disclosed |
| US-20100130733-A1 | LUMINESCENT METAL ION COMPLEXES | BIOSEARCH TECHNOLOGIES, INC. (US) | 2010-05-27 | — | — | US | disclosed |
| WO-2009071895-A1 | FUSED THIAZOLE AND THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2009-06-11 | — | — | WO | disclosed |
| EP-2029570-A1 | FUSED THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB Pharma S.A. (BE) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007141504-A1 | FUSED THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2007-12-13 | — | — | WO | disclosed |
| US-20040146895-A1 | Luminescent metal ion complexes | BIOSEARCH TECHNOLOGIES, INC. | 2004-07-29 | — | — | US | disclosed |
| WO-2004037907-A2 | LUMINESCENT METAL ION COMPLEXES | BIOSEARCH TECHNOLOGIES, INC. (US) | 2004-05-06 | — | — | WO | disclosed |
| US-6323303-B1 | POLYMERIZING DIARYLOXY COMPOUND WITH A DIHYDRIC PHENOL COMPOUND IN THE PRESENCE OF A RUTHENIUM (II) OR RUTHENIUM (III) COMPOUND OR COMPLEX; OPTIONALLY IN PRESENCE OF A TETRAALKYL AMMONIUM OR TETRAALKYL PHOSPHONIUM SALT | GENERAL ELECTRIC COMPANY | 2001-11-27 | — | — | US | disclosed |
| US-5716781-A | FORMING A SOLUTION CONTAINING AN ANALYTE COMPRISING FIRST CHEMILUMINESCENT COMPLEX AND AN INTERNAL STANDARD CONTAINING OSMIUM BIPYRIDYL COMPLEX, INDEPENDENTLY MEASURING ELECTROLUMINESCENCE EMITTED BY ANALYTE AND STANDARD | IGEN INTERNATIONAL INC. (US) | 1998-02-10 | — | — | US | disclosed |
| US-5112974-A | Targets tumor cells for radiation treatment, metal complexes with amines or imines | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1992-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040146895-A1 | Luminescent metal ion complexes | SLC30A6, SLC39A14, SLC39A3 | TDP1 4051/4885AXL 4385/4885PKM 3449/4885 |
| US-20100130733-A1 | LUMINESCENT METAL ION COMPLEXES | SLC30A6, SLC39A14, SLC39A3 | TDP1 4051/4885AXL 4385/4885PKM 3449/4885 |
| US-20120208190-A1 | LUMINESCENT METAL ION COMPLEXES | SLC30A6, SLC39A14, SLC39A3 | TDP1 4051/4885AXL 4385/4885PKM 3449/4885 |
| US-20100305066-A1 | Fused Thiophene Derivatives as Kinase Inhibitors | PIKFYVE, PI4KA, PIK3CA | TDP1 494/4885AXL 532/4885PKM 560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.