Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 3/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.32 |
| ▸ | TLR4 | O00206 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6458556 | 1.00 | KDM1A (0.35) | KDM1ACYP2C9ALDH1A1MAPTLMNA | |
| SCHEMBL6459654 | 0.94 | KDM1A (0.36) | KDM1ACYP2C9ALDH1A1MAPTLMNA | |
| SCHEMBL6459659 | 0.94 | KDM1A (0.36) | KDM1ACYP2C9ALDH1A1MAPTLMNA | |
| SCHEMBL9225434 | 0.93 | CYP2C9 (0.40) | KDM1ACYP2C9ALDH1A1MAPTLMNA | |
| SCHEMBL9225443 | 0.93 | CYP2C9 (0.40) | KDM1ACYP2C9ALDH1A1MAPTLMNA | |
| SCHEMBL9060720 | 0.93 | CYP2C9 (0.40) | KDM1ACYP2C9ALDH1A1MAPTLMNA | |
| SCHEMBL6460617 | 0.89 | KDM1A (0.46) | KDM1ACYP2C9ALDH1A1MAPTLMNA | |
| SCHEMBL6460618 | 0.89 | KDM1A (0.46) | KDM1ACYP2C9ALDH1A1MAPTLMNA | |
| SCHEMBL6452178 | 0.87 | FASN (0.33) | KDM1A | |
| SCHEMBL6452183 | 0.87 | FASN (0.33) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |