Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 4/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.34 |
| ▸ | PDE4A | P27815 | 4/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9225443 | 1.00 | CYP2C9 (0.40) | CYP2C9ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL9225434 | 1.00 | CYP2C9 (0.40) | CYP2C9ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL6458552 | 0.93 | KDM1A (0.35) | CYP2C9ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL6458556 | 0.93 | KDM1A (0.35) | CYP2C9ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL8411606 | 0.93 | KDM1A (0.34) | CYP2C9ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL8379549 | 0.93 | KDM1A (0.34) | CYP2C9ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL8411600 | 0.93 | KDM1A (0.34) | CYP2C9ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL8411574 | 0.92 | PDE4D (0.33) | CYP2C9ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL8411577 | 0.92 | PDE4D (0.33) | CYP2C9ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL8377207 | 0.92 | PDE4D (0.33) | CYP2C9ALDH1A1MAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536442-A | ELECTROOPTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-16 | — | — | US | disclosed |
| US-5456860-A | Containing liquid crystal mixture based on dielectrically positive compounds which contain polar end group with specified lipophilicity parameter | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-10-10 | — | — | US | disclosed |
| US-5389292-A | Liquid crystalline media having positive dielctric anisotropy, chemical, heat and radiation resistance, used as electro-optical displaying | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-14 | — | — | US | disclosed |
| EP-0381728-B1 | DIFLUOROMETHYL COMPOUNDS | MERCK PATENT GMBH (DE) | 1993-12-08 | — | — | EP | disclosed |
| EP-0450354-A2 | Matrix-liquid crystal display | MERCK PATENT GmbH (DE) | 1991-10-09 | — | — | EP | disclosed |
| EP-0381728-A1 | DIFLUOROMETHYL COMPOUNDS. | MERCK PATENT GMBH (DE) | 1990-08-16 | — | — | EP | disclosed |
| WO-1990001056-A1 | DIFLUOROMETHYL COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-02-08 | — | — | WO | disclosed |