Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.35 |
| ▸ | PDE2A | O00408 | 8/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6458945 | 1.00 | KDM1A (0.35) | KDM1APDE2AEPHX2SLC6A2SLC6A4 | |
| SCHEMBL6458941 | 1.00 | KDM1A (0.35) | KDM1APDE2AEPHX2SLC6A2SLC6A4 | |
| SCHEMBL5885274 | 0.95 | PDE2A (0.33) | KDM1APDE2AEPHX2 | |
| SCHEMBL5885281 | 0.95 | PDE2A (0.33) | KDM1APDE2AEPHX2 | |
| SCHEMBL6453570 | 0.88 | KDM1A (0.47) | KDM1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6453573 | 0.88 | KDM1A (0.47) | KDM1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6453577 | 0.88 | KDM1A (0.47) | KDM1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6456684 | 0.86 | PDE2A (0.34) | KDM1APDE2AEPHX2HCRTR1HCRTR2 | |
| SCHEMBL6456687 | 0.86 | PDE2A (0.34) | KDM1APDE2AEPHX2HCRTR1HCRTR2 | |
| SCHEMBL6456679 | 0.86 | PDE2A (0.34) | KDM1APDE2AEPHX2HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |