Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.32 |
| ▸ | LYPLA1 | O75608 | 1/20 | 0.31 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.31 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6452418 | 1.00 | CNR2 (0.32) | CNR2TRPV1LYPLA1LYPLA2ABHD16A | |
| SCHEMBL6452422 | 1.00 | CNR2 (0.32) | CNR2TRPV1LYPLA1LYPLA2ABHD16A | |
| SCHEMBL6458970 | 1.00 | CNR2 (0.32) | CNR2TRPV1LYPLA1LYPLA2ABHD16A | |
| SCHEMBL6459147 | 0.99 | CNR2 (0.32) | CNR2TRPV1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6459153 | 0.99 | CNR2 (0.32) | CNR2TRPV1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6451299 | 0.96 | DPP4 (0.32) | CNR2HTR2A | |
| SCHEMBL6451303 | 0.96 | DPP4 (0.32) | CNR2HTR2A | |
| SCHEMBL6457259 | 0.92 | ALDH1A1 (0.33) | MAPTSLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL6457254 | 0.92 | ALDH1A1 (0.33) | MAPTSLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL6454492 | 0.88 | CNR2 (0.34) | CNR2TRPV1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |