Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.55 |
| ▸ | F2 | P00734 | 4/20 | 0.51 |
| ▸ | F9 | P00740 | 2/20 | 0.51 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.51 |
| ▸ | F5 | P12259 | 1/20 | 0.51 |
| ▸ | PROC | P04070 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6459181 | 0.89 | F10 (0.55) | F10F2F9CTRB1F5 | |
| SCHEMBL7371791 | 0.81 | F10 (0.49) | F10F2F9CTRB1F5 | |
| SCHEMBL4654833 | 0.81 | F10 (0.57) | F10F2F9CTRB1F5 | |
| SCHEMBL4626215 | 0.80 | F10 (0.56) | F10F2F9CTRB1F5 | |
| SCHEMBL6461799 | 0.78 | LMNA (0.40) | F10MEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL1028976 | 0.77 | F10 (0.45) | F10F2F9CTRB1F5 | |
| SCHEMBL8286933 | 0.77 | F10 (0.52) | F10F2F9CTRB1F5 | |
| SCHEMBL3538971 | 0.76 | F10 (0.52) | F10F2F9CTRB1F5 | |
| SCHEMBL8267982 | 0.75 | F10 (0.48) | F10F2F9CTRB1F5 | |
| SCHEMBL8262173 | 0.74 | F10 (0.47) | F10F2F9CTRB1F5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1571154-A1 | Beta-aminoacid-derivatives as factor Xa inhibitors | Aventis Pharma Deutschland GmbH (DE) | 2005-09-07 | — | — | EP | claimed |
| EP-1571154-A1 | Beta-aminoacid-derivatives as factor Xa inhibitors | Aventis Pharma Deutschland GmbH (DE) | 2005-09-07 | — | — | EP | disclosed |