Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 3/20 | 0.60 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15295173 | 0.83 | KDM4C (0.72) | KDM6BKDM4CMAPTSMN1; SMN2RAB9A | |
| SCHEMBL3716882 | 0.81 | KDM4C (0.67) | KDM6BKDM4CSMN1; SMN2RAB9AKMT2A | |
| SCHEMBL28283057 | 0.79 | TP53 (0.43) | KDM6BKDM4CMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6450277 | 0.79 | TP53 (0.46) | KDM6BKDM4CMAPTSMN1; SMN2RAB9A | |
| SCHEMBL28054190 | 0.79 | TP53 (0.51) | KDM4CMAPTSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL2087718 | 0.78 | KDM4C (0.69) | KDM6BKDM4CMAPTSMN1; SMN2RAB9A | |
| SCHEMBL4073078 | 0.77 | TP53 (0.50) | MAPTSMN1; SMN2RAB9AALDH1A1TP53 | |
| SCHEMBL1522683 | 0.77 | MAPT (0.62) | MAPTSMN1; SMN2RAB9AALDH1A1LMNA | |
| SCHEMBL15295184 | 0.76 | KDM6B (0.72) | KDM6BKDM4CMAPTSMN1; SMN2RAB9A | |
| SCHEMBL1523353 | 0.76 | KDM4C (0.62) | KDM6BKDM4CALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560827-A1 | ANTI-INFECTIVE AGENTS | Abbott Laboratories (US) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004041818-A1 | ANTI-INFECTIVE AGENTS | ABBOTT LABORATORIES (US) | 2004-05-21 | — | — | WO | disclosed |