SCHEMBL6459648

SCHEMBL6459648

C=CC1CCC2CC(c3ccc(CC)cc3)CCC2C1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 3/20 0.33
F2R P25116 1/20 0.31
NPSR1 Q6W5P4 1/20 0.30
KDM1A O60341 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6459644 1.00 SPHK1 (0.33) SPHK1F2RNPSR1KDM1A
SCHEMBL6450688 0.89 SPHK1 (0.40) SPHK1
SCHEMBL6450691 0.89 SPHK1 (0.40) SPHK1
SCHEMBL6454331 0.84 SPHK1 (0.32) SPHK1
SCHEMBL6454338 0.84 SPHK1 (0.32) SPHK1
SCHEMBL6456756 0.84 SPHK1 (0.32) SPHK1F2R
SCHEMBL6456751 0.84 SPHK1 (0.32) SPHK1F2R
SCHEMBL6456760 0.84 SPHK1 (0.32) SPHK1F2R
SCHEMBL6451730 0.83 SLC18A3 (0.35)
SCHEMBL6451733 0.83 SLC18A3 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6913797-B1 Decahydronaphthalene derivative DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-07-05 US disclosed
EP-1108700-A1 DECAHYDRONAPHTHALENE DERIVATIVE DAINIPPON INK AND CHEMICALS, INC. (JP) 2001-06-20 EP disclosed