Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468312 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2TSHRALDH1A1TP53HTT | |
| SCHEMBL777950 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2TSHRALDH1A1TP53HTT | |
| SCHEMBL9397393 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2TSHRALDH1A1TP53HTT | |
| SCHEMBL5132709 | 0.73 | SMN1; SMN2 (0.52) | SMN1; SMN2TSHRALDH1A1TP53HTT | |
| SCHEMBL5865848 | 0.73 | SMN1; SMN2 (0.52) | SMN1; SMN2TSHRALDH1A1TP53HTT | |
| SCHEMBL9181571 | 0.70 | SMN1; SMN2 (0.48) | SMN1; SMN2TSHRALDH1A1TP53HTT | |
| SCHEMBL9397394 | 0.70 | SMN1; SMN2 (0.48) | SMN1; SMN2TSHRALDH1A1TP53HTT | |
| SCHEMBL778407 | 0.70 | SMN1; SMN2 (0.48) | SMN1; SMN2TSHRALDH1A1TP53HTT | |
| Benzene SCHEMBL1357365 | 0.68 | SMN1; SMN2 (0.46) | SMN1; SMN2TSHRALDH1A1TP53HTT | |
| SCHEMBL6461673 | 0.67 | SMN1; SMN2 (0.36) | SMN1; SMN2TSHRALDH1A1TP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050042676-A1 | Characterising polypeptides | ELECTROPHORETICS LIMITED (GB) | 2005-02-24 | — | — | US | disclosed |
| EP-1397505-A2 | CHARACTERISING POLYPEPTIDES | Xzillion GmbH & CO.KG (DE) | 2004-03-17 | — | — | EP | disclosed |
| EP-1267170-A1 | Method for characterising polypeptides | Xzillion GmbH & CO.KG (DE) | 2002-12-18 | — | — | EP | disclosed |
| WO-2002099124-A2 | CHARACTERISING POLYPEPTIDES | XZILLION GMBH & CO. KG (DE) | 2002-12-12 | — | — | WO | disclosed |