Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5132709 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2TSHRHTR6CA1CA2 | |
| SCHEMBL9397393 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2TSHRHTR6CA1CA2 | |
| SCHEMBL777950 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2TSHRHTR6CA1CA2 | |
| SCHEMBL9397394 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2TSHRHTR6CA1CA2 | |
| SCHEMBL778407 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2TSHRHTR6CA1CA2 | |
| SCHEMBL9181571 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2TSHRHTR6CA1CA2 | |
| Benzene SCHEMBL1357365 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2TSHRHTR6CA1CA2 | |
| SCHEMBL28235593 | 0.77 | HTT (0.53) | SMN1; SMN2TSHRHTR6CA1CA2 | |
| SCHEMBL30811021 | 0.77 | ALDH1A1 (0.52) | SMN1; SMN2TSHRHTR6CA1CA2 | |
| SCHEMBL27601416 | 0.77 | ALDH1A1 (0.52) | SMN1; SMN2TSHRHTR6CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101665470-A | Method for synthesizing cyclic sulphoxide imine, sulfenamide and sulfamide by stereospecificty | SHANGHAI INST ORGANIC CHEM | 2010-03-10 | — | — | CN | claimed |
| CN-1724542-A | The preparation method of [(benzene sulfonyl) difluoromethyl] trimethyl silane | SHANGHAI INST ORGANIC CHEM (CN) | 2006-01-25 | — | — | CN | claimed |
| EP-3180324-B1 | HYPERVALENT IODINE CF2CF2X REAGENTS AND THEIR USE | ETH ZUERICH (CH) | 2020-11-25 | — | — | EP | disclosed |
| US-10669250-B2 | Hypervalent iodine CF2CF2X reagents and their use | ETH ZURICH (CH) | 2020-06-02 | — | — | US | disclosed |
| US-20190040036-A1 | HYPERVALENT IODINE CF2CF2X REAGENTS AND THEIR USE | ETH ZURICH (CH) | 2019-02-07 | — | — | US | disclosed |
| US-10040812-B2 | Hypervalent iodine CF2CF2X reagents and their use | ETH ZURICH (CH) | 2018-08-07 | — | — | US | disclosed |
| US-20170233420-A1 | HYPERVALENT IODINE CF2CF2X REAGENTS AND THEIR USE | ETH ZURICH (CH) | 2017-08-17 | — | — | US | disclosed |
| EP-3180324-A1 | HYPERVALENT IODINE CF2CF2X REAGENTS AND THEIR USE | ETH Zürich (CH) | 2017-06-21 | — | — | EP | disclosed |
| WO-2016019475-A1 | HYPERVALENT IODINE CF2CF2X REAGENTS AND THEIR USE | ETH ZURICH (CH) | 2016-02-11 | — | — | WO | disclosed |
| EP-2982672-A1 | Hypervalent iodine CF2CF2X reagents and their use | ETH Zurich (CH) | 2016-02-10 | — | — | EP | disclosed |
| CN-101665470-A | Method for synthesizing cyclic sulphoxide imine, sulfenamide and sulfamide by stereospecificty | SHANGHAI INST ORGANIC CHEM | 2010-03-10 | — | — | CN | disclosed |
| US-20060052643-A1 | Nucleophilic substitution reactions of difluorormethyl phenyl sulfone with alkyl halides leading to the facile synthesis of terminal 1,1-difluoro-1-alkenes and difluoromethylalkanes | UNIVERSITY OF SOUTHERN CALIFORNIA | 2006-03-09 | — | — | US | disclosed |
| US-20060052643-A1 | Nucleophilic substitution reactions of difluorormethyl phenyl sulfone with alkyl halides leading to the facile synthesis of terminal 1,1-difluoro-1-alkenes and difluoromethylalkanes | UNIVERSITY OF SOUTHERN CALIFORNIA | 2006-03-09 | — | — | US | disclosed |
| CN-1724491-A | The difluoromethyl reaction that [(benzene sulfonyl) difluoromethyl] trimethyl silane participates in to carbonyl compound | SHANGHAI INST ORGANIC CHEM (CN) | 2006-01-25 | — | — | CN | disclosed |
| CN-1724491-A | The difluoromethyl reaction that [(benzene sulfonyl) difluoromethyl] trimethyl silane participates in to carbonyl compound | SHANGHAI INST ORGANIC CHEM (CN) | 2006-01-25 | — | — | CN | disclosed |
| CN-1724542-A | The preparation method of [(benzene sulfonyl) difluoromethyl] trimethyl silane | SHANGHAI INST ORGANIC CHEM (CN) | 2006-01-25 | — | — | CN | disclosed |
| WO-2005097739-A2 | NUCLEOPHILIC SUBSTITUTION REACTIONS OF DIFLUOROMETHYL PHENYL SULFONE WITH ALKYL HALIDES LEADING TO THE FACILE SYNTHESIS OF TERMINAL 1,1-DIFLUORO-1-ALKENES AND DIFLUOROMETHYLALKANES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2005-10-20 | — | — | WO | disclosed |
| WO-2005097739-A2 | NUCLEOPHILIC SUBSTITUTION REACTIONS OF DIFLUOROMETHYL PHENYL SULFONE WITH ALKYL HALIDES LEADING TO THE FACILE SYNTHESIS OF TERMINAL 1,1-DIFLUORO-1-ALKENES AND DIFLUOROMETHYLALKANES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2005-10-20 | — | — | WO | disclosed |
| US-20040230079-A1 | Methods for nucleophilic fluoromethylation | SOUTHERN CALIFORNIA, UNIVERSITY OF | 2004-11-18 | — | — | US | disclosed |
| WO-2004063129-A2 | METHODS FOR NUCLEOPHILIC FLUOROMETHYLATION | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2004-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233420-A1 | HYPERVALENT IODINE CF2CF2X REAGENTS AND THEIR USE | TPO, CYP4F2, FANCF | SMN1; SMN2 4869/4885TSHR 32/4885HTR6 3353/4885 |
| US-20040230079-A1 | Methods for nucleophilic fluoromethylation | PHF2, HAO2, GSTM2 | SMN1; SMN2 1470/4885TSHR 2421/4885HTR6 1076/4885 |
| US-10669250-B2 | Hypervalent iodine CF2CF2X reagents and their use | TPO, FANCF, FANCI | SMN1; SMN2 4543/4885TSHR 14/4885HTR6 4321/4885 |
| US-20190040036-A1 | HYPERVALENT IODINE CF2CF2X REAGENTS AND THEIR USE | TPO, FANCF, FANCI | SMN1; SMN2 4543/4885TSHR 14/4885HTR6 4321/4885 |
| US-20060052643-A1 | Nucleophilic substitution reactions of difluorormethyl phenyl sulfone with alkyl halides leading to the facile synthesis of terminal 1,1-difluoro-1-alkenes and difluoromethylalkanes | PFAS, FRK, PFKFB1 | SMN1; SMN2 751/4885TSHR 1041/4885HTR6 2603/4885 |
| US-10040812-B2 | Hypervalent iodine CF2CF2X reagents and their use | TPO, CYP4F2, FANCF | SMN1; SMN2 4869/4885TSHR 32/4885HTR6 3353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.