Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | TLR4 | O00206 | 2/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 4/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6460075 | 1.00 | MAOB (0.38) | MAOBMAOATLR4CXCR3HRH3 | |
| SCHEMBL7913625 | 0.89 | MAOB (0.45) | MAOBMAOAHRH3GPR84CYP2C9 | |
| SCHEMBL11996427 | 0.89 | MAOB (0.45) | MAOBMAOAHRH3GPR84CYP2C9 | |
| SCHEMBL6451679 | 0.84 | MAOB (0.43) | MAOBMAOA | |
| SCHEMBL6463567 | 0.84 | MAOB (0.43) | MAOBMAOA | |
| SCHEMBL6451681 | 0.84 | MAOB (0.43) | MAOBMAOA | |
| SCHEMBL6463565 | 0.84 | MAOB (0.43) | MAOBMAOA | |
| SCHEMBL6456036 | 0.84 | HRH3 (0.45) | HRH3 | |
| SCHEMBL6456030 | 0.84 | HRH3 (0.45) | HRH3 | |
| SCHEMBL6455507 | 0.82 | MAOB (0.48) | MAOBHRH3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |