Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11996427 | 1.00 | MAOB (0.45) | MAOBMAOAHRH3CYP2C9GPR84 | |
| SCHEMBL8451636 | 0.93 | MAOB (0.53) | MAOBMAOAGPR84CARM1PRMT6 | |
| SCHEMBL8451631 | 0.93 | MAOB (0.53) | MAOBMAOAGPR84CARM1PRMT6 | |
| SCHEMBL10899324 | 0.90 | MAOB (0.51) | MAOBMAOAHRH3CYP2C9GPR84 | |
| SCHEMBL10899319 | 0.90 | MAOB (0.51) | MAOBMAOAHRH3CYP2C9GPR84 | |
| SCHEMBL10901747 | 0.89 | MAOB (0.47) | MAOBMAOAHRH3CYP2C9GPR84 | |
| SCHEMBL10901753 | 0.89 | MAOB (0.47) | MAOBMAOAHRH3CYP2C9GPR84 | |
| SCHEMBL6460078 | 0.89 | MAOB (0.38) | MAOBMAOAHRH3CYP2C9GPR84 | |
| SCHEMBL6460075 | 0.89 | MAOB (0.38) | MAOBMAOAHRH3CYP2C9GPR84 | |
| SCHEMBL27960940 | 0.88 | MAOA (0.42) | MAOBMAOAHRH3CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106675577-B | One kind biphenyls liquid crystal compounds of base containing pyridyl end and its preparation method and application | 陕西师范大学 | 2018-10-23 | — | — | CN | disclosed |
| CN-106433689-B | One kind alkynes liquid crystal compounds of base containing pyridyl end and its preparation method and application | 陕西师范大学 | 2018-08-24 | — | — | CN | disclosed |
| CN-106675577-A | Biphenyl liquid crystal compound containing pyridine end group and preparation method and application thereof | 陕西师范大学 | 2017-05-17 | — | — | CN | disclosed |
| CN-106433689-A | Pyridine-containing terminal alkyne liquid crystal compound and preparation method and application thereof | 陕西师范大学 | 2017-02-22 | — | — | CN | disclosed |
| CN-103805208-B | Dicyclohexyl ethylene group substituted diphenylamine alkynes liquid crystalline cpd and preparation method thereof | SHAANXI NORMAL UNIVERSITY (CN) | 2015-08-19 | — | — | CN | disclosed |
| CN-103805208-A | Dicyclohexyl ethylene group substituted diphenylacetylene liquid crystal compound and preparation method thereof | UNIV SHAANXI NORMAL | 2014-05-21 | — | — | CN | disclosed |
| EP-0640578-B2 | Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition | CHISSO CORP (JP) | 2001-06-27 | — | — | EP | disclosed |
| US-6013198-A | LIQUID CRYSTALLINE COMPOUNDS MODIFIED TO HAVE A TRIFLUOROMETHYLPHENYL GROUP OR TRIFLUOROMETHOXYPHENYL GROUP AS EXAMPLE OF KNOWN TERMINAL SUBSTITUENT; CHEMICAL STABILITY, HIGH VOLTAGE HOLDING RATIO, GOOD UV STABILITY | CHISSO CORPORATION (JP) | 2000-01-11 | — | — | US | disclosed |
| EP-0640578-B1 | Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition | CHISSO CORP (JP) | 1997-11-05 | — | — | EP | disclosed |
| EP-0761799-A1 | Liquid crystalline compound substituted with fluorine containing group, liquid crystal composition, and liquid crystal display device | Chisso Corporation (JP) | 1997-03-12 | — | — | EP | disclosed |
| EP-0640578-A1 | Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition | Chisso Corporation (JP) | 1995-03-01 | — | — | EP | disclosed |