Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4354021 | 0.77 | MAPK1 (0.42) | MAPK1MAPTKMT2ACYP2C19HIF1A | |
| SCHEMBL9279074 | 0.76 | MAPK1 (0.46) | MAPK1MAPTKMT2ACYP2C19HIF1A | |
| SCHEMBL575235 | 0.76 | MAPK1 (0.46) | MAPK1MAPTKMT2ACYP2C19HIF1A | |
| SCHEMBL11000692 | 0.75 | MAPK1 (0.37) | MAPK1MAPTKMT2ACYP2C19HIF1A | |
| SCHEMBL4352236 | 0.74 | MAPK1 (0.44) | MAPK1MAPTKMT2ACYP2C19HIF1A | |
| SCHEMBL2429063 | 0.74 | ALDH1A1 (0.46) | MAPK1MAPTKMT2ACYP2C19HIF1A | |
| SCHEMBL9645659 | 0.74 | TAAR1 (0.46) | MAPK1MAPTKMT2AALDH1A1TAAR1 | |
| SCHEMBL22730217 | 0.74 | MAPK1 (0.44) | MAPK1MAPTKMT2ACYP2C19HIF1A | |
| SCHEMBL12256221 | 0.74 | MAPK1 (0.44) | MAPK1MAPTKMT2ACYP2C19HIF1A | |
| SCHEMBL42770 | 0.74 | ALDH1A1 (0.46) | MAPK1MAPTKMT2ACYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6852804-B2 | Star block copolymers and related synthetic methods | THE UNIVERSITY OF AKRON (US) | 2005-02-08 | — | — | US | claimed |
| US-20040214951-A1 | Star block copolymers and related synthetic methods | AKRON, THE UNIVERSITY OF | 2004-10-28 | — | — | US | claimed |
| EP-0265053-B1 | Living polymerization of olefins to end-functionalized polymers | KENNEDY JOSEPH PAUL (US) | 1996-10-23 | — | — | EP | disclosed |
| US-5066730-A | Catalyst is reaction product of Lewis acid and organic ether, polarization of ether bond to form a cationic carbon | THE UNIVERSITY OF AKRON (US) | 1991-11-19 | — | — | US | disclosed |
| US-4929683-A | ORGANIC ETHER, LEWIS ACID COMPLEX | UNIVERSITY OF AKRON (US) | 1990-05-29 | — | — | US | disclosed |
| EP-0265053-A2 | Living polymerization of olefins to end-functionalized polymers | Kennedy, Joseph Paul (US) | 1988-04-27 | — | — | EP | disclosed |