Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6460245 | 1.00 | LMNA (0.34) | LMNAMAPTHTTHRH3CYP2D6 | |
| SCHEMBL6452683 | 0.92 | LMNA (0.33) | LMNAMAPTHTTHRH3CYP2D6 | |
| SCHEMBL6452693 | 0.92 | LMNA (0.33) | LMNAMAPTHTTHRH3CYP2D6 | |
| SCHEMBL6453764 | 0.91 | LMNA (0.40) | LMNAMAPTHTTHRH3CYP2D6 | |
| SCHEMBL6453767 | 0.91 | LMNA (0.40) | LMNAMAPTHTTHRH3CYP2D6 | |
| SCHEMBL6454688 | 0.90 | LMNA (0.32) | LMNAMAPTHTT | |
| SCHEMBL6454692 | 0.90 | LMNA (0.32) | LMNAMAPTHTT | |
| SCHEMBL6458977 | 0.90 | LMNA (0.37) | LMNAMAPTHTTHRH3CYP2D6 | |
| SCHEMBL6458972 | 0.90 | LMNA (0.37) | LMNAMAPTHTTHRH3CYP2D6 | |
| SCHEMBL6451473 | 0.89 | LMNA (0.35) | LMNAMAPTHTTHRH3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |