SCHEMBL6460468

SCHEMBL6460468

Cc1ccc(C)c2c1C=CC2CCCC(C1C=Cc2c(C)ccc(C)c21)C([Si](C)(C)C)[Si](C)(C)C.[Y]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6460439 0.96
SCHEMBL6453499 0.93
SCHEMBL6457048 0.90
SCHEMBL3677359 0.76 NFKB1 (0.30)
SCHEMBL6461774 0.73
SCHEMBL4600169 0.72
SCHEMBL3619462 0.68
SCHEMBL28240185 0.67
SCHEMBL4629519 0.66
SCHEMBL6260418 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1049704-B1 BRIDGED METALLOCENES, PREPARATION, USE IN CATALYTIC SYSTEMS BASELL POLYOLEFINE GMBH (DE) 2005-07-27 EP disclosed
EP-1049704-A1 BRIDGED METALLOCENES, PREPARATION, USE IN CATALYTIC SYSTEMS Montell Technology Company bv (NL) 2000-11-08 EP disclosed
WO-2000031088-A1 BRIDGED METALLOCENES, PREPARATION, USE IN CATALYTIC SYSTEMS MONTELL TECHNOLOGY COMPANY BV (NL) 2000-06-02 WO disclosed