Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.42 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.31 |
| ▸ | PER2 | O15055 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6460684 | 1.00 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3TRPV3DRD2 | |
| SCHEMBL6456652 | 0.91 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3DRD2LRRK2 | |
| SCHEMBL6456648 | 0.91 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3DRD2LRRK2 | |
| SCHEMBL6460933 | 0.89 | SLC6A4 (0.37) | SLC6A4SLC6A2SLC6A3DRD2OPRL1 | |
| SCHEMBL6460930 | 0.89 | SLC6A4 (0.37) | SLC6A4SLC6A2SLC6A3DRD2OPRL1 | |
| SCHEMBL6454369 | 0.88 | OPRL1 (0.34) | SLC6A4SLC6A2SLC6A3TRPV3OPRL1 | |
| SCHEMBL6454374 | 0.88 | OPRL1 (0.34) | SLC6A4SLC6A2SLC6A3TRPV3OPRL1 | |
| SCHEMBL6460710 | 0.88 | SLC6A4 (0.36) | SLC6A4SLC6A2SLC6A3DRD2 | |
| SCHEMBL6460715 | 0.88 | SLC6A4 (0.36) | SLC6A4SLC6A2SLC6A3DRD2 | |
| SCHEMBL6458687 | 0.87 | SLC6A4 (0.35) | SLC6A4SLC6A2SLC6A3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |