Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6460797 | 1.00 | IDO1 (0.40) | IDO1CYP2C9ALDH1A1MEN1KMT2A | |
| SCHEMBL6458445 | 0.96 | IDO1 (0.38) | IDO1CYP2C9ALDH1A1MEN1KMT2A | |
| SCHEMBL6458440 | 0.96 | IDO1 (0.38) | IDO1CYP2C9ALDH1A1MEN1KMT2A | |
| SCHEMBL5684354 | 0.94 | MEN1 (0.38) | IDO1CYP2C9ALDH1A1MEN1KMT2A | |
| SCHEMBL5684358 | 0.94 | MEN1 (0.38) | IDO1CYP2C9ALDH1A1MEN1KMT2A | |
| SCHEMBL6464462 | 0.94 | CYP2C9 (0.41) | IDO1CYP2C9ALDH1A1MEN1KMT2A | |
| SCHEMBL6464465 | 0.94 | CYP2C9 (0.41) | IDO1CYP2C9ALDH1A1MEN1KMT2A | |
| SCHEMBL14525788 | 0.91 | RAB9A (0.38) | IDO1CYP2C9RAB9A | |
| SCHEMBL6453249 | 0.89 | IDO1 (0.37) | IDO1CYP2C9ALDH1A1MAPTRAB9A | |
| SCHEMBL6456369 | 0.89 | SLC6A4 (0.37) | IDO1CYP2C9ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |