⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trichloroethane SCHEMBL3833855 | 1.00 | TSHR (1.00) | — | |
| Trichloroethane SCHEMBL10482068 | 1.00 | TSHR (1.00) | — | |
| Trichloroethane SCHEMBL16434 | 1.00 | — | — | |
| Trichloroethane SCHEMBL8853751 | 0.93 | — | — | |
| Trichloroethane SCHEMBL11347390 | 0.93 | — | — | |
| Trichloroethane SCHEMBL25372481 | 0.93 | — | — | |
| Trichloroethane SCHEMBL4605092 | 0.93 | — | — | |
| Trichloroethane SCHEMBL4603454 | 0.93 | TSHR (0.86) | — | |
| Trichloroethane SCHEMBL9279232 | 0.93 | — | — | |
| Trichloroethane SCHEMBL8720044 | 0.93 | TSHR (0.86) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 873 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130230898-A1 | HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2013-09-05 | — | — | US | claimed |
| US-8404834-B2 | Hydroxyalkyl starch derivatives and process for their preparation | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2013-03-26 | — | — | US | claimed |
| EP-2231711-B1 | HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DE GMBH (DE) | 2012-11-07 | — | — | EP | claimed |
| US-20100305033-A1 | HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2010-12-02 | — | — | US | claimed |
| EP-2231711-A1 | HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION | Fresenius Kabi Deutschland GmbH (DE) | 2010-09-29 | — | — | EP | claimed |
| WO-2009077154-A1 | HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2009-06-25 | — | — | WO | claimed |
| EP-2070950-A1 | Hydroxyalkyl starch derivatives and process for their preparation | Fresenius Kabi Deutschland GmbH (DE) | 2009-06-17 | — | — | EP | claimed |
| US-7511094-B2 | 2-methylbutyraldehyde diethyl acetal end capped polyoxyethylene glycol; polyalkylene oxide, polyivnylpyrrolidone, polyvinyl alcohol, polyoxazoline etc. endcapped with polyetherpolyamine copolymers or oligomers covalently attached to diacetal tetramethylene group | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2009-03-31 | — | — | US | claimed |
| CN-1329427-C | Water soluble polymer alkanals | NEKTAR THERAPEUTICS CORP (US) | 2007-08-01 | — | — | CN | claimed |
| CN-1688631-A | Water soluble polymer alkanals | NEKTAR THERAPEUTICS AL CORP (US) | 2005-10-26 | — | — | CN | claimed |
| US-4440939-A | FROM 7-OXO-5,6-TRANS-EPOXYHEPTANOATES | SMITHKLINE BECKMAN CORPORATION (US) | 1984-04-03 | — | — | US | claimed |
| US-4387239-A | NATURALLY OCCURRING LEUKOTRIENE INTERMEDIATES, BRONCHOCONSTRICTORS | SMITHKLINE BECKMAN CORPORATION (US) | 1983-06-07 | — | — | US | claimed |
| US-4352757-A | 9-OXO-5,6-EPOXYNON-7-ENOATES AND TRIPHENYLPHOSPHORANYLIDENE UNDEC-6,9-DIENE | SMITHKLINE BECKMAN CORPORATION (US) | 1982-10-05 | — | — | US | claimed |
| EP-0001727-B1 | NEW DERIVATIVES OF 4-PHENYL-2-(2',2',2-TRICHLORETHOXYCARBOXAMIDO)-THIAZOLE USEFUL AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR THE PREPARATION OF THESE COMPOUNDS | PIERRE FABRE S.A. (FR) | 1981-11-11 | — | — | EP | claimed |
| US-4287123-A | Synthesis of thienamycin via (3SR, 4RS)-3-((RS)-1-acyloxyethyl)-2-oxo-4-azetidineacetate | MERCK & CO., INC. (US) | 1981-09-01 | — | — | US | claimed |
| US-4282148-A | Synthesis of thienamycin via esters of (3SR, 4RS)-3-[(SR)-1-hydroxyethyl]-β,2-dioxo-4-azetidinebutanoic acid | MERCK & CO., INC. (US) | 1981-08-04 | — | — | US | claimed |
| EP-0032400-A1 | (3SR, 4RS)-3-((RS)-1-hydroxyethyl)- and -((RS)-1-acyloxyethyl)-2-oxo-4-azetidineacetic acid compounds and a process for preparing the same | MERCK & CO. INC. (US) | 1981-07-22 | — | — | EP | claimed |
| US-4171421-A | FROM AROMATIC AND ALIPHATIC DICARBOXYLIC ACIDS AND UNSUBITITUTED BISPHENOLS | CIBA-GEIGY CORPORATION (US) | 1979-10-16 | — | — | US | claimed |
| US-4163099-A | DICARBOXYLIC ACID CONTAINING AMIDE SUBSTITUTED ARENE RING OR AMINO SUBSTITUTED S-TRIAZINE RING; MOLDING MATERIAL | CIBA-GEIGY CORPORATION (US) | 1979-07-31 | — | — | US | claimed |
| US-4123454-A | AROMATIC DIACIDS, DIMER ACIDS, BISPHENOL A | CIBA-GEIGY CORPORATION (US) | 1978-10-31 | — | — | US | claimed |