Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trichloroethane SCHEMBL7072287 | 0.94 | TSHR (0.75) | TSHRALDH1A1LMNACYP2E1THRB | |
| Trichloroethane SCHEMBL64609 | 0.93 | — | — | |
| Trichloroethane SCHEMBL3833855 | 0.93 | TSHR (1.00) | TSHRALDH1A1LMNACYP2E1THRB | |
| Trichloroethane SCHEMBL10482068 | 0.93 | TSHR (1.00) | TSHRALDH1A1LMNACYP2E1THRB | |
| Trichloroethane SCHEMBL16434 | 0.93 | — | — | |
| Trichloroethane SCHEMBL25372481 | 0.86 | — | — | |
| Trichloroethane SCHEMBL8720047 | 0.86 | — | — | |
| Trichloroethane SCHEMBL4605092 | 0.86 | — | — | |
| Trichloroethane SCHEMBL11347390 | 0.86 | — | — | |
| Trichloroethane SCHEMBL9279232 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1574505-B1 | 1,2,4-THIADIAZOLE COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2008-07-16 | — | — | EP | disclosed |
| US-7361675-B2 | 1,2,4-thiadiazole compounds and use thereof | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2008-04-22 | — | — | US | disclosed |
| US-20060167266-A1 | 1,2,4- thiadiazole compounds and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-07-27 | — | — | US | disclosed |
| EP-1574505-A1 | 1,2,4-THIADIAZOLE COMPOUNDS AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2005-09-14 | — | — | EP | disclosed |
| EP-0430628-B1 | Fluorine-containing copolymer composition | MITSUI PETROCHEMICAL IND (JP) | 1995-06-21 | — | — | EP | disclosed |
| US-5106895-A | Organosilicon compound as monomer; curable | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-21 | — | — | US | disclosed |
| EP-0430628-A1 | Fluorine-containing copolymer composition | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |
| US-4341842-A | Method of coating automotive parts with silicone compositions | GENERAL ELECTRIC COMPANY (US) | 1982-07-27 | — | — | US | disclosed |
| US-4233452-A | TREATMENT AND PREVENTION OF CALCIUM OXALATE UROLITHIASIS | MERCK & CO., INC. (US) | 1980-11-11 | — | — | US | disclosed |
| US-4207329-A | Derivatives of glycolic and glyoxylic acid as inhibitors of glycolic acid oxidase | MERCK & CO., INC. (US) | 1980-06-10 | — | — | US | disclosed |
| US-4037466-A | Method of regenerating a glycol-ether type inspection penetrant remover by solvent extraction | ALBURGER JAMES R | 1977-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167266-A1 | 1,2,4- thiadiazole compounds and use thereof | CBR3, CBR1, NOX3 | TSHR 95/4885ALDH1A1 518/4885LMNA 4647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.