SCHEMBL6461640

SCHEMBL6461640

CCC1CC[C@@H]2C[C@H](c3ccc(-c4cc(F)c(OC(F)(F)C(F)F)c(F)c4)cc3)CC[C@@H]2C1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6461643 1.00 FFAR4 (0.30) FFAR4
SCHEMBL6451904 0.92 CYP2C9 (0.34) FFAR4
SCHEMBL6451900 0.92 CYP2C9 (0.34) FFAR4
SCHEMBL6455142 0.90 L3MBTL1 (0.31)
SCHEMBL6455140 0.90 L3MBTL1 (0.31)
SCHEMBL6456624 0.90 ESR2 (0.32) FFAR4
SCHEMBL6456629 0.90 ESR2 (0.32) FFAR4
SCHEMBL6464919 0.89 GAA (0.32)
SCHEMBL6464915 0.89 GAA (0.32)
SCHEMBL6452906 0.89 GRIN1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6913797-B1 Decahydronaphthalene derivative DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-07-05 US disclosed
EP-1108700-A1 DECAHYDRONAPHTHALENE DERIVATIVE DAINIPPON INK AND CHEMICALS, INC. (JP) 2001-06-20 EP disclosed