Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 15/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | PRF1 | P14222 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016201 | 0.88 | ADORA1 (0.68) | ADORA1ALDH1A1HSD17B10KDM4ERXFP1 | |
| SCHEMBL1421425 | 0.85 | ADORA1 (0.56) | ADORA1ALDH1A1HSD17B10KDM4ERXFP1 | |
| SCHEMBL1421834 | 0.84 | KDM4E (0.62) | ADORA1ALDH1A1HSD17B10KDM4ERXFP1 | |
| SCHEMBL6466193 | 0.84 | ADORA1 (0.60) | ADORA1ALDH1A1HSD17B10KDM4ERXFP1 | |
| SCHEMBL7014126 | 0.82 | ADORA1 (0.65) | ADORA1ALDH1A1HSD17B10MAPK1 | |
| SCHEMBL26632985 | 0.80 | ADORA1 (0.61) | ADORA1ALDH1A1HSD17B10KDM4EMEN1 | |
| SCHEMBL12553020 | 0.79 | ADORA1 (0.56) | ADORA1ALDH1A1HSD17B10KDM4ERXFP1 | |
| SCHEMBL3549098 | 0.79 | ADORA1 (0.72) | ADORA1ALDH1A1HSD17B10KDM4EMEN1 | |
| SCHEMBL30511861 | 0.78 | PRF1 (0.58) | ADORA1ALDH1A1HSD17B10KDM4ERXFP1 | |
| SCHEMBL245940 | 0.78 | PRF1 (0.58) | ADORA1ALDH1A1HSD17B10KDM4ERXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050182105-A1 | Method of using 3-cyano-4-arylpyridine derivatives as modulators of androgen receptor function | BRISTOL-MYERS SQUIBB COMPANY | 2005-08-18 | — | — | US | claimed |
| US-20050182105-A1 | Method of using 3-cyano-4-arylpyridine derivatives as modulators of androgen receptor function | BRISTOL-MYERS SQUIBB COMPANY | 2005-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182105-A1 | Method of using 3-cyano-4-arylpyridine derivatives as modulators of androgen receptor function | NR3C2, NR4A3, NR3C1 | ADORA1 1035/4885ALDH1A1 2565/4885HSD17B10 167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.