Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6462605 | 1.00 | DRD2 (0.40) | DRD2SLC6A3KDM1AMAOAMAOB | |
| SCHEMBL6454410 | 0.99 | DRD2 (0.39) | DRD2SLC6A3KDM1AMAOAMAOB | |
| SCHEMBL6460244 | 0.99 | DRD2 (0.39) | DRD2SLC6A3KDM1AMAOAMAOB | |
| SCHEMBL6454409 | 0.99 | DRD2 (0.39) | DRD2SLC6A3KDM1AMAOAMAOB | |
| SCHEMBL6460238 | 0.99 | DRD2 (0.39) | DRD2SLC6A3KDM1AMAOAMAOB | |
| SCHEMBL6464633 | 0.96 | DRD2 (0.40) | DRD2SLC6A3KDM1AMAOAMAOB | |
| SCHEMBL6464629 | 0.96 | DRD2 (0.40) | DRD2SLC6A3KDM1AMAOAMAOB | |
| SCHEMBL6464985 | 0.96 | DRD2 (0.42) | DRD2SLC6A3L3MBTL1MAPTSPHK1 | |
| SCHEMBL6464984 | 0.96 | DRD2 (0.42) | DRD2SLC6A3L3MBTL1MAPTSPHK1 | |
| SCHEMBL6451697 | 0.95 | DRD2 (0.41) | DRD2SLC6A3L3MBTL1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |