Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.37 |
| ▸ | PPARG | P37231 | 6/20 | 0.37 |
| ▸ | PPARD | Q03181 | 6/20 | 0.37 |
| ▸ | PPARA | Q07869 | 6/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.37 |
| ▸ | TLR2 | O60603 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665800 | 0.95 | ALDH1A1 (0.48) | ALDH1A1TSHRFFAR3HDAC3HDAC1 | |
| SCHEMBL27523 | 0.95 | — | — | |
| SCHEMBL27622958 | 0.92 | — | — | |
| SCHEMBL10548245 | 0.92 | — | — | |
| SCHEMBL28170432 | 0.92 | — | — | |
| Ammonia Solution, Strong SCHEMBL27732614 | 0.92 | — | — | |
| SCHEMBL5068629 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL1371872 | 0.92 | — | — | |
| Ether SCHEMBL28411769 | 0.92 | ALDH1A1 (0.46) | ALDH1A1TSHRFFAR3HDAC3HDAC1 | |
| SCHEMBL5069424 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115933316-A | Positive photoresist composition, positive photoresist and MEMS stressed element | 广州微纳芯材料科技有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-115933316-A | Positive photoresist composition, positive photoresist and MEMS stressed element | 广州微纳芯材料科技有限公司 | 2023-04-07 | — | — | CN | disclosed |
| EP-1591501-A1 | NONAROMATIC SOLVENT TYPE COATING RESIN COMPOSITION | Mitsui Chemicals, Inc. (JP) | 2005-11-02 | — | — | EP | disclosed |