Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4982462 | 0.89 | SCD (0.46) | AOC3RAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL4875622 | 0.86 | AOC3 (0.40) | AOC3 | |
| SCHEMBL4983295 | 0.85 | AOC3 (0.42) | AOC3RAB9AALDH1A1NPC1KDM4E | |
| SCHEMBL4985427 | 0.84 | AOC3 (0.41) | AOC3RAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL4875643 | 0.84 | AOC3 (0.39) | AOC3ALDH1A1CYP1A2CYP2C9MEN1 | |
| SCHEMBL4871754 | 0.84 | AOC3 (0.51) | AOC3RAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL4877861 | 0.83 | GLS (0.48) | AOC3RAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL4875983 | 0.83 | AOC3 (0.38) | AOC3NPC1CYP1A2CYP2C9MEN1 | |
| SCHEMBL4863646 | 0.82 | AOC3 (0.47) | AOC3RAB9ANPC1MAPTRXFP1 | |
| SCHEMBL4991524 | 0.82 | AOC3 (0.40) | AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608365-A1 | METHOD FOR TREATING VASCULAR HYPERPERMEABLE DISEASE | Sucampo AG (CH) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004087138-A1 | METHOD FOR TREATING VASCULAR HYPERPERMEABLE DISEASE | SUCAMPO AG (CH) | 2004-10-14 | — | — | WO | disclosed |