Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6463292 | 1.00 | ESR2 (0.40) | ESR2PTGS2PTGS1CSNK1A1CSNK1D | |
| SCHEMBL14228618 | 0.95 | ESR2 (0.43) | ESR2PTGS2PTGS1CSNK1A1CSNK1D | |
| SCHEMBL6456610 | 0.89 | ESR2 (0.37) | ESR2PTGS2PTGS1SLC6A3SLC6A4 | |
| SCHEMBL6456611 | 0.89 | ESR2 (0.37) | ESR2PTGS2PTGS1SLC6A3SLC6A4 | |
| SCHEMBL6454025 | 0.86 | ESR2 (0.37) | ESR2PTGS2PTGS1KDM1AHRH3 | |
| SCHEMBL6454022 | 0.86 | ESR2 (0.37) | ESR2PTGS2PTGS1KDM1AHRH3 | |
| SCHEMBL6456781 | 0.86 | TAAR1 (0.41) | ESR2KDM1AMAOB | |
| SCHEMBL6456776 | 0.86 | TAAR1 (0.41) | ESR2KDM1AMAOB | |
| SCHEMBL6458694 | 0.85 | ESR2 (0.41) | ESR2KDM1AHRH3 | |
| SCHEMBL6458692 | 0.85 | ESR2 (0.41) | ESR2KDM1AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |