Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | EBP | Q15125 | 1/20 | 0.37 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6458694 | 1.00 | ESR2 (0.41) | ESR2EBPDHCR7LMNAHRH3 | |
| SCHEMBL6456390 | 0.86 | FFAR1 (0.46) | ESR2LMNAHRH3SLC18A3NPC1 | |
| SCHEMBL6456393 | 0.86 | FFAR1 (0.46) | ESR2LMNAHRH3SLC18A3NPC1 | |
| SCHEMBL6460461 | 0.85 | ESR2 (0.40) | ESR2LMNAHRH3KDM1A | |
| SCHEMBL6463289 | 0.85 | ESR2 (0.40) | ESR2HRH3KDM1A | |
| SCHEMBL6460458 | 0.85 | ESR2 (0.40) | ESR2LMNAHRH3KDM1A | |
| SCHEMBL6463292 | 0.85 | ESR2 (0.40) | ESR2HRH3KDM1A | |
| SCHEMBL16892913 | 0.84 | ESR2 (0.50) | ESR2LMNAHRH3SLC18A3MAPT | |
| SCHEMBL6457309 | 0.83 | ESR2 (0.38) | ESR2HRH3KDM1ARAB9AALDH1A1 | |
| SCHEMBL6457311 | 0.83 | ESR2 (0.38) | ESR2HRH3KDM1ARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |