Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.34 |
| ▸ | FEN1 | P39748 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6463542 | 1.00 | FASN (0.35) | FASNALOX5APFEN1HTR2AHTR2C | |
| SCHEMBL6457908 | 0.91 | FASN (0.36) | FASNALOX5APFEN1HTR2AHTR2C | |
| SCHEMBL6457917 | 0.91 | FASN (0.36) | FASNALOX5APFEN1HTR2AHTR2C | |
| SCHEMBL14036377 | 0.90 | HTR2A (0.38) | HTR2AHTR2CHTR2BTRPV3 | |
| SCHEMBL6453452 | 0.90 | CYP11B1 (0.36) | FASNALOX5APFEN1CYP11B1CYP11B2 | |
| SCHEMBL6453447 | 0.90 | CYP11B1 (0.36) | FASNALOX5APFEN1CYP11B1CYP11B2 | |
| SCHEMBL6454667 | 0.89 | FASN (0.36) | FASNTRPV3CYP3A4CYP2C9APP | |
| SCHEMBL6454665 | 0.89 | FASN (0.36) | FASNTRPV3CYP3A4CYP2C9APP | |
| SCHEMBL6455208 | 0.89 | FASN (0.38) | FASNALOX5APFEN1HTR2ATRPV3 | |
| SCHEMBL6457571 | 0.89 | FASN (0.34) | FASNALOX5APFEN1TRPV3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |