Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 5/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | USP5 | P45974 | 2/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12932031 | 0.93 | HTR2A (0.37) | HTR2AHTR2CHTR2BTRPV3SLC6A2 | |
| SCHEMBL6463545 | 0.90 | FASN (0.35) | HTR2AHTR2CHTR2BTRPV3 | |
| SCHEMBL6463542 | 0.90 | FASN (0.35) | HTR2AHTR2CHTR2BTRPV3 | |
| SCHEMBL6458483 | 0.89 | TRPV3 (0.34) | HTR2AHTR2CHTR2BTRPV3SLC6A2 | |
| SCHEMBL6458492 | 0.89 | TRPV3 (0.34) | HTR2AHTR2CHTR2BTRPV3SLC6A2 | |
| SCHEMBL6459589 | 0.89 | CYP2C9 (0.39) | HTR2AHTR2CHTR2BUSP30KDM1A | |
| SCHEMBL6459593 | 0.89 | CYP2C9 (0.39) | HTR2AHTR2CHTR2BUSP30KDM1A | |
| SCHEMBL6455032 | 0.87 | SLC6A4 (0.42) | TRPV3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6455034 | 0.87 | SLC6A4 (0.42) | TRPV3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6453347 | 0.87 | TRPV3 (0.33) | HTR2AHTR2CHTR2BTRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008143340-A1 | NEMATIC LIQUID CRYSTAL COMPOSITION AND BISTABLE NEMATIC LIQUID CRYSTAL DISPLAY | DIC CORPORATION (JP) | 2008-11-27 | — | — | WO | disclosed |