Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 9/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6464244 | 1.00 | PTGS1 (0.35) | PTGS1PTGS2MAPTGAATP53 | |
| SCHEMBL6458886 | 0.99 | PTGS1 (0.34) | PTGS1PTGS2MAPTGAATP53 | |
| SCHEMBL6458881 | 0.99 | PTGS1 (0.34) | PTGS1PTGS2MAPTGAATP53 | |
| SCHEMBL6454221 | 0.99 | PTGS1 (0.34) | PTGS1PTGS2MAPTGAATP53 | |
| SCHEMBL6454223 | 0.99 | PTGS1 (0.34) | PTGS1PTGS2MAPTGAATP53 | |
| SCHEMBL6451405 | 0.97 | PTGS1 (0.35) | PTGS1PTGS2MAPTTP53POLB | |
| SCHEMBL6451412 | 0.97 | PTGS1 (0.35) | PTGS1PTGS2MAPTTP53POLB | |
| SCHEMBL6460361 | 0.92 | GAA (0.32) | MAPTGAATP53GCGRMEN1 | |
| SCHEMBL6460364 | 0.92 | GAA (0.32) | MAPTGAATP53GCGRMEN1 | |
| SCHEMBL6459786 | 0.92 | PTGS2 (0.37) | PTGS1PTGS2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |