Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2844022 | 0.88 | BLM (0.59) | SMN1; SMN2HIF1ABLMCYP3A4HPGD | |
| SCHEMBL27616082 | 0.88 | SMN1; SMN2 (0.49) | SMN1; SMN2HIF1ABLMPPARAPPARG | |
| SCHEMBL2844025 | 0.88 | BLM (0.59) | SMN1; SMN2HIF1ABLMCYP3A4HPGD | |
| SCHEMBL4937591 | 0.88 | SMN1; SMN2 (0.66) | SMN1; SMN2HIF1ABLMPPARAPPARG | |
| SCHEMBL6464407 | 0.88 | SMN1; SMN2 (0.66) | SMN1; SMN2HIF1ABLMPPARAPPARG | |
| SCHEMBL5031241 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2HIF1ABLMPPARAPPARG | |
| SCHEMBL5844647 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2HIF1ABLMPPARAPPARG | |
| SCHEMBL5843911 | 0.87 | CYP3A4 (0.49) | SMN1; SMN2HIF1ABLMPPARAPPARG | |
| SCHEMBL5031242 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2HIF1ABLMPPARAPPARG | |
| SCHEMBL16553913 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2HIF1ABLMPPARACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132539-B2 | Melanocortin receptor ligands | THE PROCTER & GAMBLE COMPANY (US) | 2006-11-07 | — | — | US | disclosed |
| US-20060247224-A1 | Melanocortin receptor ligands | THE PROCTER & GAMBLE COMPANY | 2006-11-02 | — | — | US | disclosed |
| US-20050010031-A1 | Melanocortin receptor ligands | THE PROCTER & GAMBLE COMPANY | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050010031-A1 | Melanocortin receptor ligands | MC3R, MC5R, MC1R | SMN1; SMN2 4664/4885HIF1A 2980/4885BLM 4818/4885 |
| US-20060247224-A1 | Melanocortin receptor ligands | MC3R, MC5R, MC1R | SMN1; SMN2 4747/4885HIF1A 2905/4885BLM 4813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.