Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3921947 | 0.94 | CNR1 (0.46) | CNR1HTR2AHTR2CSLC6A4CNR2 | |
| SCHEMBL3928554 | 0.94 | CNR1 (0.46) | CNR1HTR2AHTR2CSLC6A4LMNA | |
| SCHEMBL3923383 | 0.86 | CNR1 (0.48) | CNR1HTR2AHTR2CSLC6A4MAPT | |
| SCHEMBL3931062 | 0.86 | CNR1 (0.56) | CNR1HTR2AHTR2CSLC6A4CNR2 | |
| SCHEMBL3930525 | 0.85 | PLA2G2A (0.44) | CNR1HTR2AHTR2CSLC6A4LMNA | |
| SCHEMBL3928219 | 0.84 | CNR1 (0.44) | CNR1HTR2AHTR2CSLC6A4LMNA | |
| SCHEMBL3919181 | 0.84 | CNR1 (0.48) | CNR1HTR2AHTR2CSLC6A4MAPT | |
| SCHEMBL3920985 | 0.84 | CNR1 (0.50) | CNR1HTR2AHTR2CSLC6A4CNR2 | |
| SCHEMBL13602539 | 0.82 | CNR1 (0.47) | CNR1HTR2AHTR2CSLC6A4CNR2 | |
| SCHEMBL3916522 | 0.82 | CNR1 (0.51) | CNR1HTR2AHTR2CSLC6A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583742-A1 | NOVEL CB 1 RECEPTOUR INVERSE AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-10-12 | — | — | EP | claimed |
| WO-2004060870-A1 | NOVEL CB 1 RECEPTOUR INVERSE AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-07-22 | — | — | WO | claimed |