Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 3/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CPS1 | P31327 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6464610 | 1.00 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3TSHRL3MBTL1 | |
| SCHEMBL6452153 | 0.85 | SLC6A2 (0.41) | SLC6A4SLC6A2SLC6A3L3MBTL1KDM1A | |
| SCHEMBL6452149 | 0.85 | SLC6A2 (0.41) | SLC6A4SLC6A2SLC6A3L3MBTL1KDM1A | |
| SCHEMBL6450731 | 0.84 | HTR2C (0.31) | SLC6A4SLC6A2SLC6A3TSHRMAOB | |
| SCHEMBL6450725 | 0.84 | HTR2C (0.31) | SLC6A4SLC6A2SLC6A3TSHRMAOB | |
| SCHEMBL6459089 | 0.83 | SLC6A2 (0.52) | SLC6A4SLC6A2SLC6A3TSHRL3MBTL1 | |
| SCHEMBL6459095 | 0.83 | SLC6A2 (0.52) | SLC6A4SLC6A2SLC6A3TSHRL3MBTL1 | |
| SCHEMBL6456435 | 0.83 | SLC6A4 (0.37) | SLC6A4SLC6A2SLC6A3L3MBTL1KDM1A | |
| SCHEMBL6456441 | 0.83 | SLC6A4 (0.37) | SLC6A4SLC6A2SLC6A3L3MBTL1KDM1A | |
| SCHEMBL6460569 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |